DeTOP - Dexterous Transradial Osseointegrated Prosthesis with neural control and sensory feedback
DeTOP (Dexterous Transradial Osseointegrated Prosthesis with neural control and sensory feedback) is a Research and Innovation Action funded by the European Commission under the Horizon 2020 framework programme for Research and Innovation (LEIT-ICT-24-2015, GA #687905) with 5+ M€.
DeTOP addresses the scientific, technological and clinical problem of recovery of hand function after amputation. Core of this project is the osseointegrated human-machine gateway (OHMG), a bone-anchoring technique developed and pioneered at the University of Gothenburg and Integrum AB in Sweden, able to create bidirectional links between the human and a robotic prosthesis (see video below). Within DeTOP we will translate, exploit and appraise the already proven technology for trans-humeral amputation to the most frequent case of transradial amputation. In other words we aim to develop a technology that is based on the use of osseointegration as a long-term stable solution for the direct skeletal attachment of limb prostheses, physiologically appopriate control and close-to-natural sensory feedback. The new transradial prosthesis will be assessed by three selected patients, implanted in a clinical centre, in Gothenburg, Sweden.
DeTOP is coordinated by Dr. Cipriani at Scuola Sant’Anna and involves the following European universities, research centres and SMEs: Goeteborgs Universitet, Lund Universitet, University of Essex, Prensilia Srl, Integrum AB, Centre Suisse d’Electronique de Microtechnique, Campus Biomedico University of Rome (UCBM), Istituto Ortopedico Rizzoli (IOR), INAIL.
Details and current status of the project are available on the DeTOP website.
Funder: European Commission
Grant No.: 687905
Period: 2016-2020 (48 months)
Funding (to AHA): 770 k€
Funding (total): 5.1 M€
- E. Mastinu, F. Clemente, P. Sassu, O. Aszmann, R. Brånemark, B. Håkansson, M. Controzzi, C. Cipriani, and M. Ortiz-Catalan, Grip control and motor coordination with implanted and surface electrodes while grasping with an osseointegrated prosthetic hand, Journal of NeuroEngineering and Rehabilitation, 2019;
- L. A. Celi, L. Citi, M. Ghassemi, and T. J. Pollard, The PLOS ONE collection on machine learning in health and biomedicine: Towards open code and open data, PloS ONE 14, no. 1 (2019): e0210232;
- N. Malesevic, G. Andersson, A. Björkman, M. Controzzi, C. Cipriani, C. Antfolk, Instrumented platform for assessment of isometric hand muscles contractions, Measurement Science and Technology, 2019;
- C. Günter, J. Delbeke, M. Ortiz-Catalan, Safety of long-term electrical peripheral nerve stimulation: review of the state of the art, Journal of NeuroEngineering and Rehabilitation, vol. 16, no. 1, pp. 13, 2019;
- I. Boni, J. Millenaar, M. Controzzi, M. O. Catalan, Restoring Natural Forearm Rotation in Transradial Osseointegrated Amputees, IEEE Transactions on Neural System and Rehabilitation Engineering, November 2018;
- F. Clemente, B. Håkansson, C. Cipriani, J. Wessberg, K. Kulbacka-Ortiz, R. Brånemark, K. Fredén Jansson, M. Ortiz-Catalan, Touch and Hearing Mediate Osseoperception, Scientific Reports, vol. 7, no. 45363, pp. 1-11, 2017;
- F. Montagnani, M. Controzzi, C. Cipriani, Independent Long Fingers are not Essential for a Grasping Hand, Scientific Reports, vol. 6, no. 35545, pp. 1-9, 2016.
- M. Controzzi, F. Clemente, N. Pierotti, M. Bacchereti, C. Cipriani, Evaluation of hand function trasnporting fragile objects: the Virtual Eggs Test, In Proc. of the Myoelectric Control/Powered Prosthetics Symposium, Fredericton, NB, Canada, Aug. 15-18, 2017.
- F. Montagnani, M. Controzzi, C. Cipriani, A novel passive compliant wrist with switchable stiffness, In Proc. of the Myoelectric Control/Powered Prosthetics Symposium, Fredericton, NB, Canada, Aug. 15-18, 2017.
- N. Malešević, D. Marković, G. Kanitz, M. Controzzi, C. Cipriani, C. Antfolk, Decoding of individual finger movements from surface EMG signals using Vector Autoregressive Hierarchical Hidden Markov Models (VARHHMM), In Proc. of IEEE RAS/EMBS Intl. Conf. on Rehabilitation Robotics, ICORR, London, July 17-20, 2017.