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Translational Neurorehabilitation Laboratory

Joint Lab with Institute of Neuroscience of the CNR of Pisa

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The laboratory is based on the close relationship between neuroscientists, bioengineers, neurorehabilitationists and neurologists. The laboratory is the result of a decade long collaboration between the Translational Neural Engineering Area and the Institute of Neuroscience of the CNR of Pisa.

The research areas of the joint laboratory are: Investigation of the neuroscientific basis of different types of disabilities and pathologies such as stroke, Parkinson’s disease, migraine and epilepsy; neuronal dysfunctions originating from glioma development; Development of robots for post-stroke neurorehabilitation; Fostering the bridge between scientific and technological research and clinical practice.

Current research activities include: study of brain function after stroke and glioma (anatomy, electrophysiology, behaviour); study of neural dysfunctions associated to motor symptoms in Parkinson’s disease and to photosensitive migraine;  robot-based motor rehabilitation in a rodent model of stroke; epilepsy-induced modifications of visual function; closed-loop detection and suppression of epileptic seizures.


Principal Investigator

Prof. Alberto Mazzoni


Locations and Contacts

Via Giuseppe Moruzzi, 1 - 56124 Pisa 
Phone: 050-3153206 

 


Recent Publications

  • Post-stroke spontaneous motor recovery in mice can be predicted from acute-phase local field potential using machine learning  Meneghetti, N., Lassi, M., Massa, V., Micera, S., Mazzoni, A., Alia, C., Bandini, A. (2025). APL Bioengineering 
    https://doi.org/10.1063/5.0263191

  • Rodents’ visual gamma as a biomarker of pathological neural conditions  Meneghetti, N., Vannini, E., Mazzoni, A., (2024). Journal of Physiology 
    https://doi.org/10.1113/JP283858

  • Molecular changes underlying decay of sensory responses and enhanced seizure propensity in peritumoral neurons Tantillo, E., Scalera, M., De Santis, E., Meneghetti, N., Cerri, C., Menicagli, M., Mazzoni, A., Costa, M., Mazzanti, C. M., Vannini, E., Caleo, M. (2023).
    Neuro-oncology
    https://doi.org/10.1093/neuonc/noad035

  • Environmental enrichment counteracts the effects of glioma in primary visual cortex Di Castro, M.A., Garofalo, S., De Felice, E., Meneghetti, N., Di Pietro, E., Mormino, A., Mazzoni, A., Caleo, M., Maggi, L., Limatola, C. (2022). Neurobiology of Disease 
    https://doi.org/10.1016/j.nbd.2022.105894

  • Synaptic alterations in visual cortex reshape contrast-dependent gamma oscillations and inhibition-excitation ratio in a genetic mouse model of migraine Meneghetti, N., Cerri, C., Vannini, E., Tantillo, E., Tottene, A., Pietrobon, D., Caleo, M., Mazzoni, A. (2022). The Journal of Headache and Pain 23:125
    https://doi.org/10.1186/s10194-022-01495-9

  • Disruption of layer-specific visual processing in a model of focal neocortical epilepsy Panarese, A., Vissani, M., Meneghetti, N., Vannini, E., Cracchiolo, M., Micera, S., Caleo, M., Mazzoni, A., Restani, L. (2022). Cerebral Cortex
    https://doi.org/10.1093/cercor/bhac335