The OsteoAMI project aims to improve the quality of life of people with lower limb amputations through an innovative osseointegrated prosthetic system, which eliminates the problems associated with traditional sockets and establishes a direct connection between bone and implant. This approach allows greater stability, comfort and control of the limb, significantly improving the walking experience.
A further innovation of the project is the integration of the AMI technique (Agonist-antagonist Myoneural Interface), a surgical technique in which agonist-antagonist muscle pairs are reconstructed in the residual limb, allowing more natural movements and restoring proprioception, i.e. the perception of the position and movement of the prosthesis. 
The objectives of the project can be achieved thanks to the close interdisciplinary collaboration between several partners: the Istituto Ortopedico Rizzoli (IOR), the Campus Bio-Medico di Roma (UCBM), the Istituto Italiano di Tecnologia (IIT), the Scuola Superiore Sant'Anna di Pisa (SSSA), the University of Bologna (UNIBO) and the Centro Protesi INAIL di Vigorso di Budrio. The combined contributions of these institutions ensure the combination of neuromuscular interfaces and advanced surgical solutions, enhancing artificial limb control and sensory feedback.
In particular, the Artificial Hands Area of the Scuola Superiore Sant'Anna will contribute its expertise in the development of implantable magnetic markers and related tracking systems to implement the control of an ankle prosthesis developed by the IIT research group. Integrated with the AMI technique for trans-tibial amputations, this tracking system, already successfully applied to hand prostheses, will be extended to lower limbs, with the aim of achieving a more precise and natural control of the prosthesis. 

PROMOTER: INAIL
MAIN PARTNER: Istituto Ortopedico Rizzoli
GRANT NAME: PR23-CR-P5
PERIOD AND DURATION: 2023-2026 (36 months)
SSSA FUNDING: € 220.000,00